In Arthritis Care & Research, Yun et al. report using the National Institutes of Health Patient-Reported Outcomes Measurement Information System (PROMIS) instruments in substitution for lengthier Patient-Reported Outcomes instruments such as the Routine Assessment of Patient Index Data 3 (RAPID3). 6,154 eligible patients contributed 11,275 observations using 4 PROMIS computer-adaptive testing instruments and the RAPID3. There was excellent agreement between the observed RAPID3 and predicted RAPID3 scores estimated using several PROMIS instruments. PROMIS may be used in place of RAPID3 and other patient global assessment components..